Preventing or slowing age-related cognitive decline

I took notes on Dr. Andrew Huberman’s AMA (ask me anything) — he’s the Stanford neurobiology and ophthalmology professor with a podcast on using science for many factors of well-being.

His AMAs only available to premium subscribers of the Huberman Lab Podcast. Yes, I really am that nerdy!

Dr. Huberman says that lifestyle factors can override a genetic predisposition to Alzheimer’s disease if started early enough.

He also mentioned that scientists are working on a method of early detection using visual screening.

By the way, a friend of mine defined aging as “continuing to live”. I love it.

Many of these tips are best started decades before the ages in which Alzheimer’s usually shows up, but are helpful at any age.

  1. Avoid environmental toxins: pesticides, toxins, heavy metals are neurotoxins. They damage your brain. That means eat organic food!
  2. Do not hit your head hard if at all possible. Give up risky behaviors, especially if you’ve already had one TBI.
  3. Get quality sleep at least 80 percent of the time. Deep sleep helps your brain clear toxins, and you can use sleep apps to measure this. Slightly elevating your feet seems to help. Seems to me this would work best for back sleepers, not side sleepers.
  4. Challenge yourself cognitively. It’s not just doing crosswords, it’s more like learning a new language, reading difficult material, learning new-to-you dance steps. If you don’t get frustrated, you’re not being challenged enough!
  5. Get 3 to 3.5 hours of Zone 2 cardiovascular exercise per week to increase blood flow to the brain. Zone 2 cardio includes walking, rowing, swimming, and working out on an elliptical or stationary bike.
  6. Do 20 minutes of High Intensity Interval Training (HIIT) to release catecholamines for alertness, turning on neuroplasticity.
  7. Do 5-10 sets of resistance training to offset atrophy from aging.
  8. Your brain needs acetylcholine for focus and cognition. You can get it from food (eggs, especially) or take AlphaGPC in the morning, 300-900mg. Also: nicotine gum or patches — safe nicotine. Can ask your doctor.
  9. Eat a ketogenic diet. Also fasting.
  10. Take creatine monohydrate, 5 mg per day.

New pillow recommendation

This may be a new concept for some of you, but we have posture 24/7, including when we sleep. Our bodies shape themselves to how we use them. Spending 1/3 of your life with a bad pillow is an invitation for neck pain, possibly headaches, and exacerbated jaw pain.

My profession is bodywork, and I specialize in craniosacral therapy and TMJ Relief. I’m interested in the quality of life of my clients and my readers, and that includes quality of sleep, posture, range of motion, habit change, breathing, awareness, deep relaxation…and so much more.

In the past I’ve recommended the Therapeutica Sleeping Pillow often. Nearly every person with jaw issues also has neck issues, so inquiring about sleep posture and pillows is part of my evaluation, and treating the neck is part of nearly every TMJ Relief session.

The Therapeutica pillow is what I’ve used myself for years, and I never have neck pain. It comes in 5 sizes — you measure the width of your shoulder to get the right height for side sleeping. It also supports the curve in the neck for back sleeping.

I’m still recommending it, and there’s another option now as well. Yes, it is more expensive than the Therapeutica Sleeping Pillow, but it has some qualities you may appreciate.

A client recently shared with me that she’s discovered a pillow that she just loves. She has neck, head, and jaw issues. I looked it up, and it has much going for it. It’s the Turiya Organic Latex Pillow.

It’s made of natural latex and is mold and mildew resistant. The cover is made of organic cotton. The pillow is described as “medium firm”.

The top is for side sleeping, and the bottom is for back sleeping. The ear indentations are great for side sleepers with lots of ear piercings.

The average review is 4.2 stars. I haven’t tried it myself, but my client just loves it, and she’s a savvy woman…with neck, head, and jaw issues.

It’s $118, and you can buy it in 4 interest-free installments. If you buy one, you get 15% off a second one. You can try it for 30 days (which they recommend because it may take some getting used to). It comes with a 365 day guarantee, and returns are free.

It is 5 inches high, so if your shoulders are wider than that, you can put a folded towel under it for added height.

If your shoulders are narrower than that, please don’t get this pillow! Try the Therapeutica instead.

The Therapeutica pillow comes in 5 sizes, doesn’t have ear indentations, uses one side for both side and back sleeping, costs about $80 for the average size, is firm, and comes with a 5-year guarantee that it will hold its shape. It does not have ear indentations, but it does have “valleys” to minimize pressure on the jaw for side-sleepers.

It is non-allergenic and has a 90-day return policy.

If you have a favorite pillow or have tried either of these, I’m interested in your experience.

Antioxidants may lessen severity of COVID in older people

My email this morning contained news from Science Daily that researchers have discovered the mechanics of why COVID tends to be more severe in the elderly and people with underlying conditions.

I’m no scientist, but this was something I wondered about. I’m 67 and although I don’t consider myself elderly, I am an elder. (Humor me.)

I wondered what exactly is it about being older that makes one more vulnerable. I know lots of people my age and older who are healthy and living active lives. They don’t have underlying conditions, and apart from wrinklier skin, graying hair, and joints that are a little bit stiffer, are pretty healthy and fit.

According to this research as I understand it, it’s cellular oxidation that gives the COVID virus something to latch onto.

“Our analysis suggests that greater cellular oxidation in the elderly or those with underlying health conditions could predispose them to more vigorous infection, replication and disease,” says co-author Rajinder Dhindsa, an emeritus professor of biology at McGill University.

…According to the researchers, preventing the anchor from forming could be the key to unlocking new treatments for COVID-19. One strategy, they suggest, could be to disrupt the oxidizing environment that keeps the disulfide bonds intact. “Antioxidants could decrease the severity of COVID-19 by interfering with entry of the virus into host cells and its survival afterwards in establishing further infection,” says Professor Singh.

Source: Science Daily article

Cells produce free radicals as the body processes food and reacts to the environment. If the body cannot process and remove free radicals efficiently, oxidative stress can result. Antioxidants can help prevent this.

It appears that over time, an excess of free radicals can do the kind of cellular damage that results in not only more severe cases of COVID, but also heart disease, cancer, stroke, arthritis, Parkinson’s, respiratory illness, and more.

How do you prevent oxidative stress? Avoiding inflammation, pollution, smoking, and too much UV exposure help.

You can also consume antioxidants from food. They are free-radical scavengers.

Antioxidant is a broad label for hundreds of substances that do the same thing: prevent or slow oxidative stress.

You’ve probably heard of some of them, like beta-carotene and lycopene. Each one does a specific thing, but all of them are plant-based, so it’s important to eat lots of fruits and veggies, especially the most colorful ones like berries, citrus, greens, beets, tomatoes, mangoes, etc.

Without knowing this, I learned that I was already doing a lot of things right.

  • I drink matcha every morning (green tea is a major antioxidant).
  • I eat lots of leafy greens.
  • I eat a small apple for a snack nearly every day.
  • I keep frozen berries on hand for smoothies.
  • I make and drink beet kvass (a fermented drink).
  • I cook with a lot of herbs and spices. I grow herbs and pick them right before cooking.

With supplements, more is not necessarily better, and some can interact with meds. You probably want to talk to a nutritionist first.

I hope that this is helpful. I hope you stay well, and if you get sick, that you recover well. If you want to know more, I found this article credible and helpful.

Floss regularly for longevity, plus floss recommendations

Not kidding! Flossing regularly is an indicator of longevity. Of course it’s not a guarantee. It’s just that people who are knowledgeable about the benefits of flossing and who are motivated to get/keep their mouth in great shape floss — and are more likely to take care of their health in other ways.

Plus, flossing has been found to prevent heart disease.

Face it, flossing isn’t very much fun. About the most I’ve been able to get out of it is (1) being mindful about doing it daily and seeing improvements in gum health (no tenderness and bleeding is the goal), and (2) going to the dental hygienist and her barely needing to do any scraping. In fact, last time I went, I got to skip a scaling procedure, which would have been unpleasant. It also saved me $60. Continue reading