The immune system: what is it?

How the immune system works

I am not a scientist! I’m trying to make this understandable for non-scientists like me. If I can get these basics down, so can anyone!

The first thing to know is that it’s not like other systems in the body in that it doesn’t consist of specific organs, like the digestive system, nervous system, cardiovascular system, etc. It’s bigger than that.

The immune system spreads throughout the body through the blood, bone marrow, lymph nodes, and mucosa (both mucous membranes and that surrounding organs), and more specifically, it is a key function of the thymus gland and the spleen.

The immune system works to prevent pathogens such as viruses from causing harm. There are two branches of the immune system, innate and adaptive.

The innate immune system responds first to invading pathogens. The innate response is rapid but not specialized. There are many different types of cells involved.

The adaptive immune system responds to pathogens that slip past the innate immune system, and it remembers them if exposed again. The main cell types of the adaptive immune system are T cells and B cells, which are produced in the bone marrow from stem cells. They are also called lymphocytes.

T cells recognize invaders and coordinate immune responses. They consist of killers, helpers, and messengers. They kill infected damaged cells. They produce cytokines that fight pathogenic viruses, bacteria, and fungi. When they find pathogens, they send messages to activate the rest of the immune system.

B cells produce antibodies, called Immunoglobulins (Ig) of various types. These are specific proteins in our blood that respond to and counteract specific antigens (substances in pathogens that provoke an immune response).

Both T cells and B cells can become memory cells, which persist and can recognize when an antigen appears again and create a rapid, antigen-specific immune response. For instance, having had the measles once confers immunity — if exposed again, you don’t get the measles again because your adaptive immune system recognizes and defends against it successfully. You can prove it with a blood test for measles antibodies.

This is also how vaccines work. Introduce just enough of an antigen for the body to produce antibodies, and the body becomes immune to that antigen.

We don’t have any specific immune cells for SARS-CoV-2 (the actual name of the virus; COVID-19 is the name of the illness) yet, because it is novel — new. It’s one of many coronaviruses (which can cause the common cold). Immunity to one coronavirus does not confer immunity to others…and the nature of viruses is that they mutate.

So, it seems to me, developing a vaccine against SARS-CoV-2 is like trying to hit a moving target. There are labs around the world working on a vaccine — but testing one to see if it works well and is safe enough to offer everywhere takes time, about a year from what I’ve heard…so next spring…if the virus doesn’t mutate, possibly becoming even more contagious and severe.

Medical people in the trenches are currently trying to find out whether and when people who have recovered from COVID-19 have produced enough antibodies in their blood plasma to inject in critically ill people and turn it around.

Scientists around the world are also working on a simple blood test for SARS-CoV-2 antibodies. This test would not require as much testing as a vaccine, and it could be readily available in a much shorter time frame, telling us who’s had it and who hasn’t.

Since up to 25 percent of COVID cases may be symptomless (this is the largest figure I read), many more people many have had it and become immune than we now know.

For a fascinating look at the differences between the bat immune system and humans’ immune systems that explains immunity more eloquently than I while still being understandable to non scientists, read this: https://get21stnight.com/2020/03/30/why-do-we-keep-getting-diseases-from-bats/.

The role of lifestyle

Your lifestyle is a major factor in supporting your immune system, making you healthier, possibly even conferring the ability to have that symptomless version of COVID-19 that I’m sure we all wish we had (but knowing we have it and self-quarantining so as not to spread it to people with weaker immune systems)…and having complete immunity afterwards.

Maybe even being able to donate blood plasma full of antibodies to save lives!

A healthy immune system might make the difference between a mild case and a serious case.

But since it’s new, we’re still learning.

Hygiene, diet, sleep, fresh air, exercise, the parasympathetic nervous system, and supplements all play roles in keeping your immune system working well. I intend to explore these in the coming days.

Defend yourself with impeccable hygiene

Humans got way healthier when we started washing our hands and utilizing public sewage systems and drinking clean water. Before these practices became common, a lot of people suffered and died miserably from cholera, dysentery, diarrhea, hepatitis, typhus, and other diseases spread from poor sanitation.

In the time of the coronavirus, the actions you can take to improve hygiene and reduce transmission of the virus include hand washing, coughing or sneezing into your elbow, not touching your face with unwashed hands, wearing gloves, wearing a mask, self-quarantining if exposed or ill (whether you test positive or not, given the shortage of tests), social distancing, sheltering in place, lockdowns.

This virus is very contagious! Please take care not to get exposed and not to spread it. Wash.Your.Hands and Wear.A.Mask.When.You.Go.Out.

Current coronavirus stats from Austin

This is day 4 of sheltering in place. As of last night, we had 160 cases here and one death, a woman in her 70s with significant underlying health conditions. Blessings to her family. 💚🙏🏽

It’s still affecting more people in the 20-40 age group than older people in this city with a young-skewing population.

One person at a homeless shelter has tested positive. That person is being isolated at a hotel and the 19 others exposed are also isolated and being monitored.

I’m hearing reports of customers being abusive to employees at to-go restaurants and grocery store cashiers. I hope management protects their employees and bans these people for a few days so they will be more appreciative.

I’m learning about the immune system

I have a dear friend who is my age (60+) who sn’t worried about getting sick from the coronavirus. She is a naturopath and a homeopath and is trained in a lot of other alternative health care modalities.

She has absolute faith that her immune system is so robust that she will not get sick.

I don’t quite have that much faith, even though I’m doing a lot to stay healthy, but it made me curious about immunity.

One question I have is this: how many people are positive for the virus but have no symptoms? Is this because their immune systems are so robust that the virus keeps trying to make headway, but it just can’t?

Or, possibly, could it be because they were exposed to very little of the virus, just enough to test positive, but not as much as people who get sick?

I believe the tests are binary: either you test positive or negative. (I wish everyone could be tested frequently.) The threshold for testing positive may be low if people are carrying it but symptomless.

I’m also assuming that people in close or frequent contact with those carrying or sick with the virus would have more virus in their body and be more likely to get sick. So, nursing homes. Prisons. Cruise ships. Mardi Gras. Spring breakers packing the beaches.

Packed churches at Easter?

I want to learn more about the immune system. We’re all interested now!

I’m going to investigate that and report what I find here in plain language.

Today is Day 3 of shelter in place in Austin, Texas, USA. As of last night, we have 137 known cases and no deaths.

Interestingly, the majority of cases are in people under 40. Only 19 cases are in people 60+.

Checking in

Love in the time of coronavirus

Today is Day 2 of sheltering in place in Austin, Texas. We had 119 known cases as of last night (but no deaths so far), and we know the virus is being transmitted in the community. No one I know has it so far, that I’ve heard, but friends and relatives of friends do. The number of cases will almost certainly go up over the next two or three weeks. The hope is that then the number of cases will start declining because of first, social distancing, and now, sheltering in place.

For me, this means staying home, which I have been since Saturday, and for the week before, my outings were rare. I’ve ordered groceries online and picked them up. I have a wonderful daughter who can pick items up and bring them to me. I have groceries enough to last for at least a week, and I’m keeping a list on the fridge door of the items I run out of that I can get next time I shop (which will probably be online to be delivered or picked up curbside, but I do have a mask and gloves in case I need to venture inside a store). My fridge, freezer, and nonperishable shelves are full.

I feel pretty good about my chances of getting through this without getting sick, or of being mildly ill if I do get it. I had a cold in October that was mild and lasted two days, and I couldn’t remember how long it had been since I’d previously had a cold. My immune system is robust.

However, it’s unpredictable. I’m in the 60+ population and therefore considered at risk. I do yoga and dance regularly (now doing these online), I eat healthy (organic unprocessed food mostly), and I meditate, which helps keep my nervous system more balanced rather than going into stress, which is hard on the immune system. I’m working on improving my sleep, getting more deep and REM sleep according to my Fitbit.

I take really high quality supplements from Premier Research Labs and Wellevate. (I have practitioner accounts with both that you can order through if you wish.) I have homeopathic remedies on hand too. I have health insurance should I need it, and I hope that if I do, the health care system isn’t overwhelmed and can tend to me. I’m very very fortunate and grateful.

Y’all, no one is immune. This virus targets humankind. It’s a great equalizer. It doesn’t respect fame, power, talent, or riches. Movie stars, professional athletes, famous artists, royalty, and politicians have come down with it. Because it’s novel, no one has immunity, except those who have completely recovered from it.

I’m hearing people say things like “What a year this past week has been” and “there are many days in a day.” We’re in a time of rapid change.

I believe when this pandemic is over, some aspects of our lives will not go back to the way they were. This will influence people living through it for the rest of our lives. We will not take our health for granted. We will better understand the relationship between lifestyle and health. We will require that our governments take actions that support our health over corporate profits.

Dead people don’t buy stuff.

I hope the biggest takeaway is that we humans are ALL connected through our humanity. We are all dependent on this planet for our lives. Maybe we will treat each other, and our home planet, much better.

Blessings for health, immunity, resiliency, resourcefulness, and connection. 💚🙏🏽

Preventing illness, recovering quickly

One of the most widely read posts on my blog is about recovering from a virus and recovering from adrenal exhaustion. People find it by googling because they’re trying to get well.

I want to share some good advice on preventing colds and the flu, based on what is known now. The immune system is an area of interest to researchers, but without a lot of solid conclusions, so far. What I’m sharing here is the best we know now, simplified, and now of course is when it counts.

You can prevent a lot of illness by managing your life in a way so that you experience less stress. Take care with your work and relationships, whatever stresses you. Know what you can handle and don’t be afraid to set healthy-for-you boundaries. Remember, stress turns on the bad genes as well as lowering immunity. Continue reading

Recovering from a virus, recovering from adrenal exhaustion

I awoke sick Saturday morning with a sore throat. I thought maybe it was strep throat. Drank lemon echinacea Throat Coat tea, sprayed a throat numbing liquid, and took two Alleves. Ate breakfast.

As the day progressed, I began to feel achy and chilled. Not much nasal congestion, and my throat became less sore, so it was probably not a cold. Pretty sure this was some type of influenza. The first battle of an invader with the immune system takes place in the tonsils, right? They fought hard, thank you very much, but were overpowered by a virus.

Sigh. Who knows how long this will last?

I did whatever I could think of to boost my immune system. I drank Tulsi tea, then made tea from fresh ginger steeped in hot filtered water and drank that. I ate a clove of garlic. (Slice thinly and swallow quickly, don’t chew.)

I did EFT three times. I did the thymus thump several times. I took three long naps. I had no appetite at all but stayed hydrated with the teas and water.

I finally remembered I owned a thermometer and took my temperature Saturday night. It was 102.2 degrees F.

That evening was the worst of it. I couldn’t lie still. Kept needing to flex and point my feet and circle my ankles, changing position often. Weird, huh? All I can figure out is that these movements were activating meridians (several of which begin or end at the feet) and moving lymph.

(Lymph is a fluid that contains infection-fighting white blood cells. The lymphatic system clears the toxins, waste, and other stuff  your body no longer needs. It’s a key part of the body’s immune system. Since the lymphatic system doesn’t have a pump, it works better when you take measures to help it circulate: by moving the body, dry-brushing, and lymphatic drainage, a type of light massage.)

I’ve learned in my studies of trauma recovery to allow the body to move as it needs to, unless it’s dangerous. So on with the foot movements.

Sunday morning I felt a bit better. Took my temperature twice that day, 99 in a.m., 100 in p.m. Aches and chills were gone, and my appetite came back somewhat later in the day, but my energy was low. I decided to stay home yesterday (Monday), believing that resting would speed my full recovery.

It seems I had a mini-virus, a two-day bout of illness. I have no idea if what I did shortened the duration of it, or if it would have been a 48-hour bug no matter what. You’d need a scientific experiment with a control group to determine that, and there could still be variables unaccounted for.

Still, it just feels better to know that I did what I could to strengthen my immune system.

Today (Tuesday) my temperature was normal. I went out and did a few things that couldn’t be postponed (I’m moving on Friday, after all), but I still feel weak and not quite back to myself.  I’m accustomed to feeling well and having a nice level of energy.

I have so much to do this week, it’s imperative that I recover quickly. I need to clean out my shed, get boxes, pack, and work three days this week. I need to get well. I made an acupuncture appointment because it helps.

~~~

Postscript, July 9, 2012. Hindsight is such a great teacher, bringing the gifts of perspective and insight.

When I look back on the time when I originally wrote this post a year and a half ago, I can see that I was stressed. I was selling my house, moving, and starting a new contract job. That’s when I got sick.

Stress weakens the immune system. If it goes on too long, you can suffer from adrenal depletion or exhaustion.

That happened to me this spring. I had just just studied for and passed the national certification exam for massage and bodywork, not exercising or resting enough, and I was stressing about money and work. A friend suddenly showed distinct signs of mental illness, which freaked me out. I experienced a fight-or-flight reaction, which means the adrenals are producing copious amounts of stress hormones that keep the sympathetic nervous system dominant.

I took different contract job at a technology company, working in a group that was experiencing a lot of chaos, with an hour-long commute. Much more stress and misery.

No wonder, when I saw my acupuncturist after the job ended, she told me I was suffering from adrenal exhaustion.

She advised me to take over-the-counter high quality rhodiola and eleuthero as directed on the bottles to recover from the adrenal exhaustion. I’ve been doing that for about a month now, and I feel much better. (These are also listed on my Products I Recommend page.)

As a massage therapist, I recommend frequent massage to help the body release stress and tension. A relaxing massage helps the nervous system begin to regulate itself again instead of being stuck in sympathetic mode, which helps you recover from stress more quickly and experience the deep relaxation (and strong immune system, better digestion, better sleep, stronger sex drive, more playful attitude) that occur when the parasympathetic nervous system comes back online. I also recommend Epsom salt baths for stress relief.

Related: See my post about preventing illness and recovering quickly.